如下：

To disable Transparent HugePages boot time either one of the following 2 methods may be used:

Add the following to the kernel boot line in /etc/grub.conf (a symlink to /boot/grub/grub.conf) and reboot the server (this is the preferred method):

[size=90%]transparent_hugepage=never

Once modified the line will read similar to the following example:

[size=90%]title Oracle Linux Server (2.6.32-300.25.1.el6uek.x86_64)
root (hd0,0)
kernel /vmlinuz-2.6.32-300.25.1.el6uek.x86_64 ro root=LABEL=/ transparent_hugepage=never
initrd /initramfs-2.6.32-300.25.1.el6uek.x86_64.img

[size=90%]

OR

Add the following lines in /etc/rc.local and reboot the server (this still can be done on Redhat 7 although rc.local is being deprecated):

[size=90%]if test -f /sys/kernel/mm/transparent_hugepage/enabled; then echo never > /sys/kernel/mm/transparent_hugepage/enabledfiif test -f /sys/kernel/mm/transparent_hugepage/defrag; then echo never > /sys/kernel/mm/transparent_hugepage/defragfi

Please change the file path for RHEL kernel to /sys/kernel/mm/redhat_transparent_hugepage/ accordingly.